Table 1 Demographic, clinical, and laboratory values of 181,879 hemodialysis patients according to dialyzer type
Variable | I | II | III | IV | V | P value |
|---|---|---|---|---|---|---|
n (%male) | 1506 (47.0) | 3277 (49.6) | 10,689 (56.8) | 97,927 (62.1) | 68,480 (71.2) | < 0.0001 |
Age, years | 77.8 ± 9.8 | 77.4 ± 10.1 | 73.3 ± 11.5 | 70.9 ± 11.8 | 66.2 ± 12.1 | < 0.0001 |
Vintage, months | 46 (19–101) | 46 (21–98) | 53 (23–109) | 61 (28–121) | 79 (38–145) | < 0.0001 |
Cause of ESKD, % | < 0.0001 | |||||
Diabetic nephropathy | 38.9 | 38.2 | 40.3 | 39.9 | 39.5 | |
Chronic glomerulonephritis | 26.8 | 24.1 | 26.7 | 29.0 | 31.8 | |
Nephrosclerosis | 15.3 | 15.1 | 13.9 | 12.6 | 10.8 | |
Others | 19.0 | 22.6 | 19.1 | 18.5 | 17.9 | |
Diabetes mellitus, % | 56.8 | 57.2 | 56.3 | 54.2 | 53.9 | < 0.0001 |
Comorbid CVD, % | 41.2 | 42.7 | 35.7 | 35.2 | 31.7 | < 0.0001 |
Systolic BP, mmHg | 146 ± 27 | 147 ± 27 | 149 ± 25 | 150 ± 25 | 152 ± 24 | < 0.0001 |
Diastolic BP, mmHg | 73 ± 15 | 73 ± 15 | 75 ± 14 | 76 ± 14 | 79 ± 15 | < 0.0001 |
Heart rate, bpm | 74 ± 13 | 73 ± 13 | 74 ± 13 | 74 ± 13 | 75 ± 13 | < 0.0001 |
Body mass index, kg/m2 | 19.4 ± 3.5 | 19.7 ± 3.5 | 20.8 ± 3.8 | 21.3 ± 3.9 | 22.3 ± 4.2 | < 0.0001 |
Serum urea nitrogen, mg/dL | 56.4 ± 18.7 | 55.5 ± 17.5 | 59.6 ± 16.5 | 59.6 ± 15.8 | 61.4 ± 15.4 | < 0.0001 |
Creatinine, mg/dL | 7.0 ± 2.7 | 7.4 ± 2.7 | 8.7 ± 2.7 | 9.4 ± 2.8 | 10.6 ± 2.7 | < 0.0001 |
β2-microglobulin, mg/L | 31.1 ± 11.6 | 30.1 ± 9.9 | 27.5 ± 7.4 | 26.9 ± 6.9 | 27.3 ± 6.3 | < 0.0001 |
Kt/V | 1.31 ± 0.31 | 1.35 ± 0.31 | 1.46 ± 0.31 | 1.47 ± 0.31 | 1.49 ± 0.30 | < 0.0001 |
Serum albumin, g/dL | 3.1 ± 0.6 | 3.2 ± 0.6 | 3.5 ± 0.5 | 3.5 ± 0.5 | 3.6 ± 0.4 | < 0.0001 |
Hemoglobin, g/dL | 10.4 ± 1.5 | 10.5 ± 1.4 | 10.7 ± 1.3 | 10.8 ± 1.3 | 10.9 ± 1.3 | < 0.0001 |
C-reactive protein, mg/dL | 0.30 (0.09–1.15) | 0.25 (0.08–0.90) | 0.19 (0.07–0.60) | 0.16 (0.06–0.50) | 0.14 (0.05–0.41) | < 0.0001 |
Calcium, mg/dL | 8.5 ± 0.8 | 8.5 ± 0.8 | 8.6 ± 0.8 | 8.7 ± 0.7 | 8.7 ± 0.7 | < 0.0001 |
Phosphate, mg/dL | 4.8 ± 1.7 | 4.8 ± 1.5 | 5.0 ± 1.5 | 5.1 ± 1.4 | 5.3 ± 1.5 | < 0.0001 |
Intact-PTH, pg/mL | 108 (54–194) | 110 (57–188) | 126 (67–205) | 127 (69–205) | 136 (77–215) | < 0.0001 |
nPCR, g/kg/day | 0.77 ± 0.20 | 0.77 ± 0.19 | 0.84 ± 0.18 | 0.84 ± 0.18 | 0.86 ± 0.17 | < 0.0001 |